Chargers stun Kansas City in Sao Paulo, riding a career-highlight performance from Justin Herbert to a 27-21 victory and ending a 7-game slide against the Chiefs. Herbert threw for 318 yards with 3 TDs and added a 19-yard scrambling dagger on 3rd-and-14 to seal it, a moment that screams fantasy pedigree. Quentin Johnston injected life with 5 catches, 79 yards and 2 scores, signaling a real breakthrough. Keenan Allen reaffirmed elite target share with 7 receptions and a TD, while Najee Harris barely touched the ball. The win clears the path for a high-flying LA attack as Week 2 against the Raiders looms.

Rookie Tre Harris and Ladd McConkey flashed in supportive roles for LA, while the veteran Allen and the budding Johnston present a top-5 fantasy trio in an offense that can big-play its way to weekly upside. KC didn’t get the usual Mahomes fireworks, but the Chargers proved they can win games through schemed plays and Herbert’s accuracy. The result reshapes early-season projections as the Chargers head into their MNF showpiece and fantasy managers recalibrate expectations for LA’s weapons.

Adonai Mitchell could finally break out in Year 2 with Indianapolis, leveraging top-line Open Score insights that showed him among the league leaders in downfield openness last season. A more stable QB situation—Daniel Jones in Week 1, plus the presence of Pittman and a promising rookie tight end Tyler Warren—could unlock Mitchell’s big-play ability. Jonathan Taylor’s ground game should keep defenses honest, boosting scoring opportunities for the receiving corps.

Mitchell’s path hinges on improved connection timing and a quieter field for deep routes. If he compounds his open-ness with better quarterback accuracy and cleaner downfield throws, expect a meaningful jump from a quiet rookie campaign to a confident sophomore season, with Colts’ scoring potential rising accordingly.

Gronkowski believes New England is in a very different place than a year ago, thanks to a revamped staff led by Vrabel and a mix of veteran and rookie additions. The hinge is Drake Maye, entering year two, but the offensive line must hold up. Will Campbell anchors the blind side, Jared Wilson and Garrett Bradbury protect the interior, with Morgan Moses at right tackle, while Mike Onwenu returns at right guard. If the line stabilizes, Maye could unlock a higher-powered offense than last season’s four-win campaign.

Gronk’s main caveat is OL play. If the protection holds, Maye will have time to connect with a growing receiver corps and push New England toward a markedly improved 2025 product. The Patriots’ fate hinges on trench play, development from Maye, and the ability to translate offseason upgrades into on-field success.

Tampa Bay may bring Keenan Isaac back after Cleveland released him, aiming to fortify a CB corps stretched by injuries. Isaac’s familiarity with Bowles’ system and preseason flashes give him immediate emergency-rotation value behind Dean and McCollum, with a low-cost path to a roster spot as final cuts loom.

Depth behind the starters remains unsettled, and Isaac’s potential reunion hinges on whether the Buccaneers prioritize known quantity over upside. His size and scheme fit are appealing, but limited long-term consistency and minimal special-teams impact temper expectations.